Expresión de búsqueda: KETOL-ACID REDUCTOISOMERASE 
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Descriptor Inglés:   Ketol-Acid Reductoisomerase 
Descriptor Español:   Cetoácido Reductoisomerasa 
Descriptor Portugués:   Cetol-Ácido Redutoisomerase 
Categoría:   D08.811.682.047.820.487
Definición Inglés:   An enzyme that catalyzes the oxidation of (R)-2,3-dihydroxy-3-methylbutanoate to (S)-2-hydroxy-2-methyl-3-oxobutanoate in the presence of NADP. It is involved in the biosynthesis of VALINE; LEUCINE; ISOLEUCINE; pentothenate and COENZYME A. This enzyme was formerly classified as EC 1.1.1.89. 
Nota Histórica Inglés:   2006(1980); use VALERATES 1970-1979 
Calificadores Permitidos Inglés:  
AD administration & dosage AE adverse effects
AN analysis AI antagonists & inhibitors
BI biosynthesis BL blood
CF cerebrospinal fluid CS chemical synthesis
CH chemistry CL classification
CT contraindications DF deficiency
DE drug effects EC economics
GE genetics HI history
IM immunology IP isolation & purification
ME metabolism PK pharmacokinetics
PD pharmacology PH physiology
PO poisoning RE radiation effects
SE secretion ST standards
SD supply & distribution TU therapeutic use
TO toxicity UL ultrastructure
UR urine  
Número del Registro:   50599 
Identificador Único:   D050540 

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